Giuliana De Sio was born in Salerno and grew up in Cava de 'Tirreni, where her family originates from. De Sio's first public appearance was her when she was five in a show at the Teatro Verdi in Salerno. She moved to Terrasini when she was eighteen to live in a hippy commune before moving to Rome, where she befriended Teresa Ann Savoy and Alessandro Haber, who encouraged her to start acting. Her professional debut took place in 1976 when Gianni Bongiovanni chose her for Una donna. Elio Petri then gave her a part of her in Mani dirty di lei and Tonino Cervi chooses her to act in The Imaginary Sick with Alberto Sordi.
In the early 1980s she meets Massimo Troisi, who chooses her for an important role in her second film, Sorry for the delay (1982). She subsequently worked with Francesco Nuti in The Pool Hustlers (1982) and Casablanca Casablanca (1985).
2024
2023
as Self (archive footage)
2022
2020
as Self (archive footage)
2017
as Roberta
2017
as Tina
2017
as Annalisa Bottelli
2014
as Isabella Colbran
2014
as Irma Voglino
2014
as Alla Nazimova
2012
as Madre di Enzo
2012
2011
2010
as Self
2010
as Bigiù
2008
as Armida Casoni
2006
as Laura
2006
as Concetta De Nicola
2006
as Lara
2005
as Concetta Melita 'Cetty' Saponero dal Puozzo
2004
as Elena Monti
2002
as Elena
2001
as Annalisa Bottelli Renzi Di Balsano
2000
as Erodiade
1998
as Iris
1997
as Dr. Sophia Minardi
1996
as Margherita
1994
1992
1992
as Wanda Treptow
1992
as Sandra
1991
as Emilia
1990
as Alix/Clara
1988
as Teresa Capece
1987
as Nagra
1987
as Rosario, the prostitute
1986
as Franca
1985
as Chiara
1984
as Giulia Canella
1984
as Maestrina dalla penna rossa
1984
as Emanuela Setti Carraro
1984
as Giulia Antinari
1983
as Chiara
1983
as Anna
1979
as Angelica
1979
as Luisa
1978
as Jessica
1976
as Cesira
1948
as Self