'Toon star Roger is worried that his wife Jessica is playing pattycake with someone else, so the studio hires detective Eddie Valiant to snoop on her. But the stakes are quickly raised when Marvin Acme is found dead and Roger is the prime suspect.
as Eddie Valiant
as Judge Doom
as Dolores
as Roger Rabbit / Benny The Cab / Greasy / Psycho (voice)
as Jessica Rabbit (voice)
as Marvin Acme
as R.K. Maroon
as Lt. Santino
as Baby Herman (voice)
as Jessica's Performance Model
as Raoul
as Augie
as Angelo
as Arthritic Cowboy
as Soldier
as Stretch
as Editor / Gorilla (voice)
as Kid #1
as Kid #2
as Kid #3
as Blonde Starlet
as Forensic #1
as Forensic #2
as Mailman
as Newscaster
as Conductor
as Teddy Valiant
as Mrs. Herman (voice)
as Betty Boop (voice)
as Daffy Duck / Tweety / Bugs Bunny / Sylvester / Porky Pig (voice)
as Donald Duck (voice)
as Hippo (voice)
as Yosemite Sam / Foghorn Leghorn (voice)
as Smart Ass (voice)
as Stupid (voice)
as Wheezy / Lena Hyena (voice)
as Mickey Mouse (voice)
as Minnie Mouse / Birds (voice)
as Mr. Toad (voice)
as Droopy (voice)
as Bullet #1 (voice)
as Bullet #2 (voice)
as Bullet #3 (voice)
as Singing Sword (voice) (archive sound)
as Goofy / Big Bad Wolf (voice)
as Pinocchio (voice)
as Woody Woodpecker
as Additional Voices (voice) (uncredited)
as Mime (uncredited)
as Judge Doom (high-pitched voice) (voice) (uncredited)
as Dipped Shoe (voice) (uncredited)
as Jessica Rabbit (singing voice) (uncredited)
as Mooing Cow / Flying Witch (voice) (uncredited)
as Dumbo (voice) (uncredited)
as Ink and Paint Club Patron (uncredited)