A pathologist experiments with a deaf-mute woman who is unable to scream to prove that humans die of fright due to an organism he names The Tingler that lives within each person on the spinal cord and is suppressed only when people scream when scared.
as Dr. Warren Chapin
as Oliver 'Ollie' Higgins
as Mrs. Martha Ryerson Higgins
as David Morris
as Lucy Stevens
as Isabel Stevens Chapin
as Prologue Host (uncredited)
as Ryerson - Screaming Convict (uncredited)
as Projectionist (uncredited)
as Member of Silent Movie Audience (uncredited)
as Member of Silent Movie Audience (uncredited)
as David Kinemon (archive footage) (uncredited)
as Member of Silent Movie Audience (uncredited)
as Member of Silent Movie Audience (uncredited)
as Member of Silent Movie Audience (uncredited)
as Member of Silent Movie Audience (uncredited)
as Member of Silent Movie Audience (uncredited)
as Luke Hatburn (archive footage) (uncredited)