Peter Parker is an outcast high schooler abandoned by his parents as a boy, leaving him to be raised by his Uncle Ben and Aunt May. Like most teenagers, Peter is trying to figure out who he is and how he got to be the person he is today. As Peter discovers a mysterious briefcase that belonged to his father, he begins a quest to understand his parents' disappearance – leading him directly to Oscorp and the lab of Dr. Curt Connors, his father's former partner. As Spider-Man is set on a collision course with Connors' alter ego, The Lizard, Peter will make life-altering choices to use his powers and shape his destiny to become a hero.
as Spider-Man / Peter Parker
as Gwen Stacy
as The Lizard / Dr. Curt Connors
as Captain Stacy
as Uncle Ben
as Aunt May
as Rajit Ratha
as Richard Parker
as Mary Parker
as Flash Thompson
as Peter Parker (Age 4)
as Jack's Father
as Jack
as Helen Stacy
as Store Clerk
as Cash Register Thief
as Gordon
as Missy Kallenback
as Hot Girl
as Mr. Cramer
as Physics Nerd
as Physics Nerd
as Miss Ritter
as School Librarian
as Nicky's Girlfriend
as Nicky
as Car Thief
as Car Thief Cop
as Receptionist
as OsCorp Intern
as Rodrigo Guevara
as Howard Stacy
as Philip Stacy
as Simon Stacy
as Construction Worker
as Taxi Driver
as Police Officer with Sketch
as Police Officer
as Officer (SWAT)
as Sheila (Subway)
as Subway Guy
as Newscaster (News Chopper)
as Principal
as Second Girl (Subway)
as Man in the Shadows
as Ariel
as Scientist (uncredited)
as Lab Technician (uncredited)
as Billy Connors (uncredited)
as Cheerleader (uncredited)
as Goth Girl (uncredited)
as Tina (uncredited)
as Alfie (uncredited)